The year is 2096. In the wake of the 2nd Huffman Conflict's true causes becoming public in 2092, the world has turned its back on the Republic of Zaftra. Foreign investment dried up, businesses withdrew, and major powers like the United States of the New Continent refused to import Zaftra's resources. The Peace Mediation Organization was disbanded in 2094 as Zaftra's economy collapsed inward. Then, without warning, Zaftra launches a lightning offensive against European Community military bases, pushing Europe toward a resource crisis. Simultaneously, Venezuela declares independence from the USN. Front Mission 4 follows two interlocking storylines across Venezuela and Europe as opposing forces race to contain — or ignite — a new world conflict.