JoJo's Bizarre Adventure: Heritage for the Future

Drawn from the manga's third arc, Stardust Crusaders, the game centers on Japanese teenager Jotaro Kujo, who has awakened a supernatural power called a "Stand." His grandfather, Joseph Joestar, reveals that this ability stems from the influence of the Joestar family's sworn enemy, the vampire Dio. When Jotaro's mother begins manifesting a Stand she can't control and her life falls into danger, Jotaro and Joseph set out on a quest to destroy Dio and save her.