In The Stetchkov Syndicate, players once again lead an element of the Fairview SWAT team, this time pitted against the titular crime syndicate that smuggles illegal drugs and weapons into the city. The first mission has the team responding to a shootout in progress at a video arcade in a rundown neighborhood, where they learn the city's drug dealers now face fearsome new competition.
Soon after, the team handles a group of failed robbers barricaded inside a halfway house. The plot deepens when it becomes clear someone is supplying assault weapons and explosives to a range of buyers, including a Christian fundamentalist cult and a band of irate farmers. The Fairview team then targets the Stetchkov clan directly, beginning with a raid on a drug lab the Stetchkovs run out of an abandoned house. Things grow more complicated when the syndicate and a rival gang battle each other at a subway station, catching many civilians in the crossfire. After SWAT restores order, they serve a search warrant at a warehouse owned by a Stetchkov front company, where they capture the clan's leadership and end its reign of terror.