Ryu Hayabusa returns as a master ninja caught in a conflict that draws in allies from across multiple factions, each with their own reasons to fight. Beyond Ryu's main quest, the story expands through separate campaigns featuring Ayane, a skilled kunoichi from the peaceful Mugen Tenshin clan; Momiji, a naginata-wielding member of Ryu's own bloodline; and Rachel, a cursed warrior from the Holy Vigoor Empire who hunts fiends despite bearing their dark power within herself. Together, their intersecting paths reveal different angles of a larger struggle that threatens multiple ninja clans and supernatural forces alike.