A brilliant but unhinged European scientist named Dr. Curien has pushed the boundaries of genetic experimentation far beyond ethical limits, transforming his sprawling mansion into a laboratory of horrors where mutated creatures roam freely. When AMS agent Thomas Rogan learns that his fiancée Sophie has been trapped within the estate, he and his partner G launch a desperate rescue mission into the nightmare facility on December 18, 1998. Armed with knowledge of the creatures' vulnerabilities documented in a scientist's journal, the two agents must fight through waves of genetically engineered abominations while uncovering the truth behind Curien's twisted obsession with conquering death itself.