On the corporate war-torn planet of Promethea, three strangers are thrown together when the Tediore corporation launches a violent siege. Anuradha "Anu" Dhar is an idealistic Atlas scientist just fired over her non-lethal invention; her estranged adopted brother Octavio dreams of fame and fortune; and Fran runs a struggling frozen-yogurt shop with the help of an assassination bot named L0U13. As Tediore forces tear the city apart hunting them, the trio reluctantly bands together and follows a trail into a hidden Vault, chasing a discovery that could change their fortunes forever, if they survive the corporations closing in around them.