Dr. Ryuji Hirasaka is a genius physician with a severe personality disorder and no interest in patients except as material for his personal experiments. When he receives a temporary posting at St. Juliana Hospital, he arrives to find a former victim waiting for him: Narumi Jinguji. She has a proposal that stops him cold. Her goal is to build the most corrupt hospital ward in the world, and she wants Hirasaka to help her assemble the perfect team to run it. The appeal of finally pursuing his most twisted professional ambitions without resistance is too much to walk away from. Whether St. Juliana becomes the den of mad science he envisions, or whether his own abrasiveness and incompetence doom the Night Shift before it begins, is the question.