Mad scientist Genius Yamada has begun his bid for world domination by seizing control of a game machine at the You&Me Kamiyoga arcade in Setagaya-ku, Tokyo. Yuki Ito, a clerk at the arcade, refuses to let the crisis unfold on her shift. She throws together a makeshift coalition—literally piecing together her own collection of game boards and recruiting the protagonists from each game—to defeat Yamada before the situation escalates further.