In the neon-drenched metropolis of Harbor Prime, a secretive corporate alliance called the Complex maintains iron-fisted control over every citizen and system. When a young woman named Dex suddenly becomes the target of assassination squads without understanding why, she's rescued by an enigmatic hacker who introduces her to an underground resistance movement working to dismantle the Complex's stranglehold on the city. As Dex navigates both the gritty streets and the digital realms hidden beneath them, she pursues various missions that can be tackled in multiple ways while gradually piecing together the mystery of her own importance to those hunting her.