In a fantasy Japan where same-sex romance is unremarkable and a nurse's touch can literally heal pain, cheerful new graduate Kaori Sawai joins the staff of Yurigahama Hospital. A childhood near-death experience left Kaori with a gift — her hands relieve suffering in patients through direct contact — and an unshakeable desire to help others. Nurse Love Syndrome shares its world with Nurse Love Addiction, with a script co-written by nurses Sakura Sakura and Madoka Madoka, focusing on young adults navigating the early years of a medical career alongside stories of love and growth.