S.E.M.I.: Side Effects May Include...

S.E.M.I.: Side Effects May Include...

Released2026
S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.
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Details

DeveloperTwo Horn Unicorn
ReleasedJanuary 23, 2026
StatusReleased
GenresHack and slash/Beat 'em upIndieArcade
ThemesActionComedyParty
PlatformsPC (Microsoft Windows) PC (Microsoft Windows)
ModesMultiplayerSingle playerCo-operative

About This Game

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Players Online

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